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Article

Integrative genomic analysis focused on cell cycle genes for MYC-driven aggressive mature B-cell lymphoma.

Journal of clinical and experimental hematopathology : JCEH - 1 Jan 2020

Yamashita Takahisa, Vollbrecht Claudia, Hirsch Burkhard, Kleo Karsten, Anagnostopoulos Ioannis, Hummel Michael

Abstract excerpt

MYC is a transcriptional factor that regulates growth and proliferation through cell cycle pathways. MYC alterations, in particular MYC rearrangements, are important in assessing the prognosis of aggressive B-cell lymphoma. In this study, we focused on the impact of nine major cell cycle genes for MYC-driven aggressive mature B-cell lymphoma and analyzed the mutational status using targeted next generation...

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Share to Cell Cycle
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Gene Rearrangement

Share to Lymphoma, B-Cell

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Share to Proto-Oncogene Proteins c-myc

Source

Open in PubMed Open full text

Identifiers

PMID: 32981916
DOI: 10.3960/jslrt.20021
PMCID: PMC7596913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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