Article
Insights into the dN/dS ratio heterogeneity between brain specific genes and widely expressed genes in species of different complexity.
Genomics - 1 Jul 2016
Biswas Kakali, Chakraborty Sandip, Podder Soumita, Ghosh Tapash Chandra
Abstract excerpt
In mammals, it has long been suggested that brain-specific genes (BSGs) and widely expressed genes (WEGs) have seemingly lower dN/dS ratio than any other gene sets. However, to what extent these genes differ in their dN/dS ratio has still remained controversial. Here, we have revealed lower dN/dS ratio of BSGs than WEGs in human-mouse, human-orangutan, human-chimpanzee and mouse-rat orthologous pair. The...
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