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Article

Polycythemia vera: from new, modified diagnostic criteria to new therapeutic approaches.

Clinical advances in hematology & oncology : H&O - 1 Sept 2017

Maffioli Margherita, Mora Barbara, Passamonti Francesco

Abstract excerpt

Polycythemia vera (PV) is a Philadelphia chromosome-negative chronic myeloproliferative neoplasm that is associated with a Janus kinase 2 (JAK2) mutation in most cases. The most recent update to the World Health Organization diagnostic criteria for PV was published in 2016. These were the modifications with the greatest effect: (1) lowering the hemoglobin threshold, allowing a diagnosis of PV at 16.5 g/dL in...

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Identifiers

PMID: 28949941

Genes

CALR
JAK2

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