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Article

The role of TLR9 polymorphism in susceptibility to pulmonary tuberculosis.

Immunogenetics - 1 Dec 2014

Bharti Deepak, Kumar Ashish, Mahla Ranjeet Singh, Kumar Sushil, Ingle Harshad, Shankar Hari, Joshi Beenu, Raut Ashwin Ashok, Kumar Himanshu

Abstract excerpt

Mycobacterium tuberculosis (MTB) is the causative agent of pulmonary tuberculosis (PTB), a major health problem that leads to 1.5 million deaths annually. Host genetic factors play a significant role in disease resistance/susceptibility by altering immunity against MTB. Toll-like receptor (TLR) sensors such as TLR2, TLR4, TLR8, and TLR9 are known to play a pivotal role in PTB via modulating sensor expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25248338
DOI: 10.1007/s00251-014-0806-1

Genes

TLR9
MAF
TLR2
TLR4
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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