Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the Pattern Recognition Receptor Mincle Gene (CLEC4E) and Association with Tuberculosis.

Lung - 1 Oct 2016

Bowker Nicholas, Salie Muneeb, Schurz Haiko, van Helden Paul D, Kinnear Craig J, Hoal Eileen G, Möller Marlo

Abstract excerpt

The mechanisms involved in interactions between Mycobacterium tuberculosis and host innate immune cells determine outcome. Antigen-presenting cells, including macrophages and dendritic cells, express many pattern recognition receptors to identify pathogen-associated molecular patterns, thereby initiating an immune response. A major mycobacterial virulence factor, trehalose-6',6-dimycolate, is recognised by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins, C-Type

Share to Mycobacterium tuberculosis

Share to Polymorphism, Single Nucleotide

Share to Receptors, Immunologic

Share to Tuberculosis, Pulmonary

Share to Young Adult

Source

Identifiers

PMID: 27363694
DOI: 10.1007/s00408-016-9915-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the Pattern Recognition Receptor Mincle Gene (CLEC4E) and Association with Tuberculosis.PMID 27363694Read ↗

CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa).Semantic proximity Read ↗

Innate immune gene polymorphisms in tuberculosis.Semantic proximity Read ↗

Host genome polymorphisms and tuberculosis infection: What we have to say?Semantic proximity Read ↗

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity.Semantic proximity Read ↗

Legionella pneumophila modulates macrophage functions through epigenetic reprogramming via the C-type lectin receptor MincleSemantic proximity Read ↗

C-type lectin receptors in tuberculosis: what we know.Semantic proximity Read ↗

Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL.Semantic proximity Read ↗

A Functional Toll-Interacting Protein Variant Is Associated with Bacillus Calmette-Guérin-Specific Immune Responses and Tuberculosis.Semantic proximity Read ↗

A case-control study on correlation between the single nucleotide polymorphism of CLEC4E and the susceptibility to tuberculosis among Han people in Western China.Semantic proximity Read ↗

The influence of single nucleotide polymorphisms of NOD2 or CD14 on the risk of Mycobacterium tuberculosis diseases: a systematic review.Semantic proximity Read ↗

Towards a crucial role for DC-SIGN in tuberculosis and beyond.Semantic proximity Read ↗

Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.