Article
Interactions Between Genome-Wide Genetic Factors and Smoking Influencing Risk of Systemic Lupus Erythematosus.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Nov 2020
Cui Jing, Raychaudhuri Soumya, Karlson Elizabeth W, Speyer Cameron, Malspeis Susan, Guan Hongshu, Sparks Jeffrey A, Ni Hongru, Liu Xinyi, Stevens Emma, Williams Jessica N, Davenport Emma E, Knevel Rachel, Costenbader Karen H
Abstract excerpt
OBJECTIVE: To identify interactions between genetic factors and current or recent smoking in relation to risk of developing systemic lupus erythematosus (SLE). METHODS: For the study, 673 patients with SLE (diagnosed according to the American College of Rheumatology 1997 updated classification criteria) were matched by age, sex, and race (first 3 genetic principal components) to 3,272 control subjects without a...
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