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Article

Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity.

Cell reports - 22 Sept 2020

Leylek Rebecca, Alcántara-Hernández Marcela, Granja Jeffrey M, Chavez Michael, Perez Kimberly, Diaz Oscar R, Li Rui, Satpathy Ansuman T, Chang Howard Y, Idoyaga Juliana

Abstract excerpt

Human dendritic cells (DCs) comprise subsets with distinct phenotypic and functional characteristics, but the transcriptional programs that dictate their identity remain elusive. Here, we analyze global chromatin accessibility profiles across resting and stimulated human DC subsets by means of the assay for transposase-accessible chromatin using sequencing (ATAC-seq). We uncover specific regions of chromatin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32966789
DOI: 10.1016/j.celrep.2020.108180
PMCID: PMC7546547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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