IsoResolve: predicting splice isoform functions by integrating gene and isoform-level features with domain adaptation.

Abstract excerpt

MOTIVATION: High resolution annotation of gene functions is a central goal in functional genomics. A single gene may produce multiple isoforms with different functions through alternative splicing. Conventional approaches, however, consider a gene as a single entity without differentiating these functionally different isoforms. Towards understanding gene functions at higher resolution, recent efforts have focused...

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