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Epigenetic Regulation in Mesenchymal Stem Cell Aging and Differentiation and Osteoporosis

10 Sept 2020

Abstract excerpt

Mesenchymal stem cells (MSCs) are a reliable source for cell-based regenerative medicine owing to their multipotency and biological functions. However, aging-induced systemic homeostasis disorders in vivo and cell culture passaging in vitro induce a functional decline of MSCs, switching MSCs to a senescent status with impaired self-renewal capacity and biased differentiation tendency. MSC functional decline...

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Mesenchymal stem cell research
MicroRNA in disease regulation
Telomeres, Telomerase, and Senescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32963550
DOI: 10.1155/2020/8836258

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