Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseases

16 May 2022

Abstract excerpt

As global aging accelerates, the prevention and treatment of age-related bone diseases are becoming a critical issue. In the process of senescence, bone marrow mesenchymal stem cells (BMSCs) gradually lose the capability of self-renewal and functional differentiation, resulting in impairment of bone tissue regeneration and disorder of bone tissue homeostasis. Alteration in epigenetic modification is an essential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Histone Deacetylase Inhibitors Research
Share to Mesenchymal stem cell research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35578312
DOI: 10.1186/s13287-022-02852-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseasesPMID 35578312Read ↗

Epigenetic control of mesenchymal stem cells orchestrates bone regenerationSemantic proximity Read ↗

Rejuvenation of Mesenchymal Stem Cells to Ameliorate Skeletal AgingSemantic proximity Read ↗

Epigenetic Regulation in Mesenchymal Stem Cell Aging and Differentiation and OsteoporosisSemantic proximity Read ↗

Age-related Changes in Bone Marrow Mesenchymal Stromal CellsSemantic proximity Read ↗

Impact of Environmental and Epigenetic Changes on Mesenchymal Stem Cells during AgingSemantic proximity Read ↗

Epigenetic regulation of mesenchymal stem cell aging through histone modificationsSemantic proximity Read ↗

Mechanisms and therapeutic strategies linking mesenchymal stem cells senescence to osteoporosisSemantic proximity Read ↗

Cellular senescence and other age-related mechanisms in skeletal diseasesSemantic proximity Read ↗

Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissuesSemantic proximity Read ↗

Skeletal Aging and Osteoporosis: Mechanisms and TherapeuticsSemantic proximity Read ↗

Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axisSemantic proximity Read ↗

Molecular Basis of Bone AgingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.