Article
Microenvironmental Views on Mesenchymal Stem Cell Differentiation in Aging.
Journal of dental research - 1 Nov 2016
Sui B D, Hu C H, Zheng C X, Jin Y
Abstract excerpt
Aging is characterized by common environmental changes, such as hormonal, immunologic, and metabolic disorders. These pathologic factors impair the capability of mesenchymal stem cells (MSCs) to generate and maintain functionalized tissue components, contributing to age-related tissue degeneration (e.g., osteoporosis). However, in organismal aging, whether the microenvironmental signals induce common or...
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