Article

Epigenetic adaptation prolongs photoreceptor survival during retinal degeneration

2019-09-18

Abstract excerpt

Neural degenerative diseases often display a progressive loss of cells as a stretched exponential distribution. The mechanisms underlying the survival of a subset of genetically identical cells in a population beyond what is expected by chance alone remains unknown. To gain mechanistic insights underlying prolonged cellular survival, we used Spata7 mutant mice as a model and performed single-cell transcriptomic p...

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Literature Corpus work: 1fa9f5d5-42c4-53b9-b99f-be2fda02d954
DOI: 10.1101/774950

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