Article

Mechanism-driven screening of membrane-targeting and pore-forming antimicrobial peptides

2025-05-21

Abstract excerpt

The rise of antibiotic resistance has generated an urgent demand for the discovery of new antimicrobial peptides (AMPs), prompting the development of various screening strategies. However, the specific function mechanisms of AMPs are often overlooked during the screening and optimization processes. In this study, we introduce a mechanism-driven screening approach that employs machine learning-based computational m...

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Literature Corpus work: 40ab76c3-66ad-51f3-a7f0-9cd114dade04
DOI: 10.1101/2025.05.17.654650

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