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Article

Variants of genes encoding TNF receptors and ligands and proteins regulating TNF activation in familial multiple sclerosis.

CNS neuroscience & therapeutics - 1 Nov 2020

Torre-Fuentes Laura, Matías-Guiu Jordi A, Pytel Vanesa, Montero-Escribano Paloma, Maietta Paolo, Álvarez Sara, Gómez-Pinedo Ulises, Matías-Guiu Jorge

Abstract excerpt

INTRODUCTION: Numerous genetic variants have been associated with susceptibility to multiple sclerosis (MS). Variants located in genes involved in specific pathways, such as those affecting TNF-α, can contribute to the risk of MS. The purpose of this study was to determine whether variants of these genes are associated with greater risk of MS. METHODS: We used whole-exome sequencing to study genes coding for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32951330
DOI: 10.1111/cns.13456
PMCID: PMC7564193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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