Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer.

doi:10.1158/1078-0432.CCR-20-2268

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Article

Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2020

Richard François, Majjaj Samira, Venet David, Rothé Françoise, Pingitore Julien, Boeckx Bram, Marchio Caterina, Clatot Florian, Bertucci François, Mariani Odette, Galant Christine, Eynden Gert van den, Salgado Roberto, Biganzoli Elia, Lambrechts Diether, Vincent-Salomon Anne, Pruneri Giancarlo, Larsimont Denis, Sotiriou Christos, Desmedt Christine

Abstract excerpt

PURPOSE: Invasive lobular carcinoma (ILC) represents the second most common histologic breast cancer subtype after invasive ductal carcinoma (IDC). While primary ILC has been extensively studied, metastatic ILC has been poorly characterized at the genomic and immune level. EXPERIMENTAL DESIGN: We retrospectively assembled the multicentric EuroILC series of matched primary and metastatic samples from 94 patients...

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PMID: 32943456
DOI: 10.1158/1078-0432.CCR-20-2268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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