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Article

Damage patterns observed in mtDNA control region MPS data for a range of template concentrations and when using different amplification approaches.

International journal of legal medicine - 1 Jan 2021

Holland Charity A, McElhoe Jennifer A, Gaston-Sanchez Sidney, Holland Mitchell M

Abstract excerpt

Massively parallel sequencing (MPS) of mitochondrial (mt) DNA allows practitioners the ability to fully resolve heteroplasmic sites. In forensic DNA analysis, identifying heteroplasmy (a naturally occurring mixture of two mtDNA profiles) can provide additional mtDNA profile information which can lead to an increase in the discrimination potential of an mtDNA match between an evidentiary sample and reference...

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Share to DNA Damage
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 32940843
DOI: 10.1007/s00414-020-02410-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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