Article
An optimized protocol for forensic application of the PreCR™ Repair Mix to multiplex STR amplification of UV-damaged DNA.
Forensic science international. Genetics - 1 Jul 2012
Diegoli Toni M, Farr Matthew, Cromartie Carter, Coble Michael D, Bille Todd W
Abstract excerpt
Damage to the DNA molecule can occur through exposure to environmental conditions such as ultraviolet light, heat and humidity. Forensic samples are particularly prone to such damage due to their prolonged exposure after deposition at crime scenes or mass disasters. Current methods for typing such samples rely heavily on the intact DNA template, and can be adversely affected by damage that is present. Proposed...
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