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Article

Comparative tolerance of two massively parallel sequencing systems to common PCR inhibitors.

International journal of legal medicine - 1 Jul 2018

Elwick Kyleen, Zeng Xiangpei, King Jonathan, Budowle Bruce, Hughes-Stamm Sheree

Abstract excerpt

Human remains can be severely affected by the environment, and the DNA may be damaged, degraded, and/or inhibited. In this study, a DNA sample (at 1 ng DNA target input in triplicate) was spiked with five concentrations of five inhibitors (humic acid, melanin, hematin, collagen, and calcium) and sequenced with both the HID-Ion AmpliSeq™ Library Kit and ID panel on the Ion PGM™ System and the ForenSeq DNA...

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PMID: 28956146
DOI: 10.1007/s00414-017-1693-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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