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Mitochondrial DNA Variation in Human Hair Shafts Influenced by Physical Characteristics: A Massively Parallel Sequencing Analysis.

Genes - 13 Jul 2026

Wang Nana, Liu Jiajun, Peng Dan, Geng Jiaojiao, Wu Enlin, Liang Hui, Wu Riga, Li Ran, Sun Hongyu

Abstract excerpt

BACKGROUND/OBJECTIVES: Hair shafts are frequently encountered as forensic evidence, but their limited nuclear DNA content often constrains short tandem repeat (STR) profiling. Mitochondrial DNA (mtDNA) analysis provides an alternative approach; however, the extent to which hair-shaft physical characteristics affect MPS-derived mtDNA read counts, degradation state, and point heteroplasmy (PHP) remains...

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Share to DNA, Mitochondrial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42510836
DOI: 10.3390/genes17070796
PMCID: PMC13409926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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