Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

2-APB-potentiated channels amplify CatSper-induced Ca2+ signals in human sperm

4 Sept 2012

Abstract excerpt

Ca2+i signalling is pivotal to sperm function. Progesterone, the best-characterized agonist of human sperm Ca2+i signalling, stimulates a biphasic [Ca2+]i rise, comprising a transient and subsequent sustained phase. In accordance with recent reports that progesterone directly activates CatSper, the [Ca2+]i transient was detectable in the anterior flagellum (where CatSper is expressed) 1-2 s before responses in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Healthcare and Venom Research
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22943284
DOI: 10.1042/bj20120339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

2-APB-potentiated channels amplify CatSper-induced Ca2+ signals in human spermPMID 22943284Read ↗

CatSper: The complex main gate of calcium entry in mammalian spermatozoaSemantic proximity Read ↗

[Ca2+]i oscillations in human sperm are triggered in the flagellum by membrane potential-sensitive activity of CatSperSemantic proximity Read ↗

Membrane potential and feedback dynamics regulate CatSper-mediated progesterone signaling in human spermSemantic proximity Read ↗

Mobilisation of stored calcium in the neck region of human sperm a mechanism for regulation of flagellar activitySemantic proximity Read ↗

Reassessing the role of progesterone in fertilization—compartmentalized calcium signalling in human spermatozoa?Semantic proximity Read ↗

The CatSper channel mediates progesterone-induced Ca2+ influx in human spermSemantic proximity Read ↗

Progesterone Accelerates the Completion of Sperm Capacitation and Activates CatSper Channel in Spermatozoa from the Rhesus Macaque1Semantic proximity Read ↗

Regulation and roles of Ca2+ stores in human spermSemantic proximity Read ↗

The Chemosensing Role of CatSper in Mammalian Sperm: An Updated ReviewSemantic proximity Read ↗

[Ca2+]i signalling in sperm — making the most of what you've gotSemantic proximity Read ↗

Calcium Signaling Through CatSper Channels in Mammalian FertilizationSemantic proximity Read ↗

Revisiting the action of steroids and triterpenoids on the human sperm Ca2+ channel CatSperSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.