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Article

Anti-tumor immunity influences cancer cell reliance upon ATG7

1 Jan 2020

Abstract excerpt

Macroautophagy (autophagy) is an essential cellular catabolic process required for survival under conditions of starvation. The role of autophagy in cancer is complex, context-dependent and at times contradictory, as it has been shown to inhibit, promote or be dispensable for tumor progression. In this study, we evaluated the contribution of the immune system to the reliance of tumors on autophagy by depleting...

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Share to Autophagy in Disease and Therapy
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Identifiers

PMID: 32923161
DOI: 10.1080/2162402x.2020.1800162

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