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Article

The functions of autophagy at the tumour‐immune interface

18 Feb 2021

Abstract excerpt

Autophagy is frequently induced in the hypoxic tumour microenvironment. Accumulating evidence reveals important functions of autophagy at the tumour-immune interface. Herein, we propose an update on the roles of autophagy in modulating tumour immunity. Autophagy promotes adaptive resistance of established tumours to the cytotoxic effects of natural killer cells (NKs), macrophages and effector T cells. Increased...

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PMID: 33605033
DOI: 10.1111/jcmm.16331

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