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Autophagy in tumor immune escape and immunotherapy

19 Mar 2025

Abstract excerpt

The immunotherapy targeting tumor immune escape mechanisms has become a critical strategy in anticancer treatment; however, the challenge of immune resistance remains significant. Autophagy, a cellular response to various stressors, involves the degradation of damaged proteins and organelles via lysosomal pathways, maintaining cellular homeostasis. This process not only supports tumor cell survival but also...

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PMID: 40102867
DOI: 10.1186/s12943-025-02277-y

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