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Autophagy and cancer – insights from mouse models

18 Sept 2017

Abstract excerpt

(Macro-)autophagy is an evolutionary conserved 'self-digestion program' that serves to maintain cellular metabolism and is implicated in many pathological processes such as cancer. In recent years, an increasing number of studies in murine cancer models have provided a plethora of sometimes conflicting results about the role of autophagy in cancer biology. This review summarizes these studies and raises awareness...

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PMID: 28921866
DOI: 10.1111/febs.14274

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