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Article

Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt-Jakob disease.

Acta neuropathologica - 1 Dec 2020

Dabin Luke C, Guntoro Fernando, Campbell Tracy, Bélicard Tony, Smith Adam R, Smith Rebecca G, Raybould Rachel, Schott Jonathan M, Lunnon Katie, Sarkies Peter, Collinge John, Mead Simon, Viré Emmanuelle

Abstract excerpt

Prion diseases are fatal and transmissible neurodegenerative disorders caused by the misfolding and aggregation of prion protein. Although recent studies have implicated epigenetic variation in common neurodegenerative disorders, no study has yet explored their role in human prion diseases. Here we profiled genome-wide blood DNA methylation in the most common human prion disease, sporadic Creutzfeldt-Jakob...

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Identifiers

PMID: 32918118
DOI: 10.1007/s00401-020-02224-9
PMCID: PMC7666287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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