Article
Dutch population structure across space, time and GWAS design.
Nature communications - 11 Sept 2020
Byrne Ross P, van Rheenen Wouter, van den Berg Leonard H, Veldink Jan H, McLaughlin Russell L
Abstract excerpt
Previous genetic studies have identified local population structure within the Netherlands; however their resolution is limited by use of unlinked markers and absence of external reference data. Here we apply advanced haplotype sharing methods (ChromoPainter/fineSTRUCTURE) to study fine-grained population genetic structure and demographic change across the Netherlands using genome-wide single nucleotide...
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