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Article

The Real-Life Data of BRAF Mutation on the Treatment of Colorectal Cancer: a TOG Study.

Journal of gastrointestinal cancer - 1 Sept 2021

Beypinar Ismail, Demir Hacer, Sakin Abdullah, Taskoylu Burcu Yapar, Sakalar Teoman, Ergun Yakup, Korkmaz Mustafa, Ates Ozturk, Eren Tulay, Turhal Serdar, Artac Mehmet

Abstract excerpt

PURPOSE: Colorectal cancer is the third leading diagnosis accounting for nearly 10% of all new cancers worldwide. The distinct features among BRAF mutant colorectal cancers make these tumor groups hard to treat for oncologists. The median overall survival (OS) of these types of cancers is reported to be 9 to 14 months. METHODS: The study was declared on the Turkish Oncology Study Group Conference and approved....

Topics

Aged
Antineoplastic Combined Chemotherapy Protocols
Biomarkers, Tumor
Colorectal Neoplasms
Female
Fluorouracil
Genes, ras
Humans
Leucovorin
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Organoplatinum Compounds

Proto-Oncogene Proteins B-raf

Survival Rate

Turkey

Source

Identifiers

PMID: 32914373
DOI: 10.1007/s12029-020-00514-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32914373-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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