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Article

Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study.

Clinical colorectal cancer - 1 Mar 2018

Kayhanian Hamzeh, Goode Emily, Sclafani Francesco, Ang Joo Ern, Gerlinger Marco, Gonzalez de Castro David, Shepherd Scott, Peckitt Clare, Rao Sheela, Watkins David, Chau Ian, Cunningham David, Starling Naureen

Abstract excerpt

BACKGROUND: Somatic v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutation, present in approximately 10% of metastatic colorectal cancer (mCRC) cases, is associated with poor prognosis. Patient outcome outside of clinical trials has only been reported in small series. We report real-world data on treatment and survival for BRAF-mutated (MT) patients at a single tertiary center, compared with a matched BRAF...

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Source

Identifiers

PMID: 29129559
DOI: 10.1016/j.clcc.2017.10.006

Genes

BRAF
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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