Article
Real-world treatment and outcomes of patients with metastatic BRAF mutant colorectal cancer.
Cancer medicine - 1 May 2023
Xu Ting, Li Jian, Wang Zhenghang, Zhang Xiaotian, Zhou Jun, Lu Zhihao, Shen Lin, Wang Xicheng
Abstract excerpt
BACKGROUND: BRAF mutation occurs in 5%-10% of metastatic colorectal cancers (mCRCs). Patients with BRAF mutant mCRC exhibit a specific metastatic pattern and poor prognosis. Survival outcomes are heterogeneous in cases of mCRC with a BRAF mutation. The optimal first-line therapy is still controversial. METHODS: We retrospectively reviewed the medical records of patients with mCRC between June 2010 and December...
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