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Article

Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors.

The American journal of surgical pathology - 1 Feb 2021

Baillard Pauline, Genestie Catherine, Croce Sabrina, Descotes Françoise, Rouleau Etienne, Treilleux Isabelle, Gouy Sebastien, Morice Philippe, Ray-Coquard Isabelle, McCluggage W Glenn, Devouassoux-Shisheboran Mojgan

Abstract excerpt

FOXL2 somatic mutation occurs in a high percentage of ovarian adult granulosa cell tumors and DICER1 mutations in a high proportion of Sertoli-Leydig cell tumors. These mutations have only been studied in a limited number of juvenile granulosa cell tumors (JGCTs), and their occurrence and frequency in these neoplasms is controversial. We aimed to determine the frequency of FOXL2 and DICER1 mutations in a large...

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Identifiers

PMID: 32910017
DOI: 10.1097/PAS.0000000000001582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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