Article
DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.
Histopathology - 1 Jan 2016
Goulvent Thibault, Ray-Coquard Isabelle, Borel Stéphane, Haddad Véronique, Devouassoux-Shisheboran Mojgan, Vacher-Lavenu Marie-Cecile, Pujade-Laurraine Eric, Savina Ariel, Maillet Denis, Gillet Germain, Treilleux Isabelle, Rimokh Ruth
Abstract excerpt
AIMS: FOXL2 mutation has been consistently identified in adult granulosa cell tumours (A-GCTs). DICER1 mutations have been described predominantly in Sertoli-Leydig cell tumours (SLCTs). The prognostic implication of these mutations remains uncertain, as moderately sized studies have yielded variable outcomes. Our aim was to determine the implications of DICER1 and FOXL2 mutations in 156 ovarian sex cord-stromal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
