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Article

DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry.

Gynecologic oncology - 1 Dec 2017

Schultz Kris Ann P, Harris Anne K, Finch Michael, Dehner Louis P, Brown Jubilee B, Gershenson David M, Young Robert H, Field Amanda, Yu Weiying, Turner Joyce, Cost Nicholas G, Schneider Dominik T, Stewart Douglas R, Frazier A Lindsay, Messinger Yoav, Hill D Ashley

Abstract excerpt

BACKGROUND: Ovarian sex cord-stromal tumors (OSCST) include juvenile granulosa cell tumors (JGCT), Sertoli-Leydig cell tumor (SLCT) and gynandroblastoma (GAB) among others. These ovarian sex cord-stromal tumors as well as other tumors including pleuropulmonary blastoma (PPB) may be associated with DICER1 mutations. We sought to describe the clinical and genetic findings from the first 107 individuals enrolled in...

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Identifiers

PMID: 29037807
DOI: 10.1016/j.ygyno.2017.09.034
PMCID: PMC5716477

Genes

DICER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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