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Article

Corded and Hyalinized Endometrioid Adenocarcinoma (CHEC) of the Uterine Corpus are Characterized by CTNNB1 Mutations and Can Show Adverse Clinical Outcomes.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Mar 2021

Ladwig Nicholas R, Umetsu Sarah E, Zaloudek Charles, Rabban Joseph, Garg Karuna

Abstract excerpt

Corded and hyalinized endometrioid adenocarcinoma (CHEC) is a morphologic variant of endometrioid adenocarcinoma that is typically low-grade [International Federation of Gynecology and Obstetrics (FIGO) grade 1-2]. CHEC exhibits a biphasic appearance with gland forming adenocarcinoma merging with a diffuse component with corded growth often in a hyalinized matrix; squamous differentiation is frequent and osteoid...

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PMID: 32909971
DOI: 10.1097/PGP.0000000000000671

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