Article
BCOR is a robust diagnostic immunohistochemical marker of genetically diverse high-grade endometrial stromal sarcoma, including tumors exhibiting variant morphology.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2017
Chiang Sarah, Lee Cheng-Han, Stewart Colin J R, Oliva Esther, Hoang Lien N, Ali Rola H, Hensley Martee L, Arias-Stella Javier A, Frosina Denise, Jungbluth Achim A, Benayed Ryma, Ladanyi Marc, Hameed Meera, Wang Lu, Kao Yu-Chien, Antonescu Cristina R, Soslow Robert A
Abstract excerpt
Recognition of high-grade endometrial stromal sarcoma is important because of its aggressive clinical behavior. Morphologic features of YWHAE-NUTM2 high-grade endometrial stromal sarcoma may overlap with other uterine sarcoma types. BCOR immunoexpression was studied in these tumors and their morphologic mimics to assess its diagnostic utility. BCOR immunohistochemical staining was performed on archival tissue...
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