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Hepatitis B virus preS2Δ38–55 variants: A newly identified risk factor for hepatocellular carcinoma

11 Jul 2020

Abstract excerpt

BACKGROUND & AIMS: Although HBV is a major cause of death in Africa, its genetic variability has been poorly documented. This study aimed to address whether HBV genotype and surface gene variants are associated with HBV-related liver disease in The Gambia. METHODS: mutation was determined by NGS in circulating cell-free plasma DNA. RESULTS: <0.001), with preS2 deletions between nucleotides 38-55 (preS2Δ38-55)...

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PMID: 32904132
DOI: 10.1016/j.jhepr.2020.100144

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