Article
Technical report: Targeted proteomic analysis reveals enrichment of atypical ubiquitin chains in contractile murine tissues
6 Sept 2020
Abstract excerpt
Ubiquitylation is an elaborate post-translational modification involved in all biological processes. Its pleotropic effect is driven by the ability to form complex polyubiquitin chain architectures that can influence biological functions. In this study, we optimised sample preparation and chromatographic separation of Ubiquitin peptides for Absolute Quantification by Parallel Reaction Monitoring (Ub-AQUA-PRM)....
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