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Article

Optimizing the Use of iPSC-CMs for Cardiac Regeneration in Animal Models

2 Sept 2020

Abstract excerpt

Heart failure (HF) is a common disease in which the heart cannot meet the metabolic demands of the body. It mostly occurs in individuals 65 years or older. Cardiac transplantation is the best option for patients with advanced HF. High numbers of patient-specific cardiac myocytes (CMs) can be generated from induced pluripotent stem cells (iPSCs) and can possibly be used to treat HF. While some studies found...

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PMID: 32887495
DOI: 10.3390/ani10091561

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