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Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells: Current Strategies and Limitations.

31 Jul 2018

Abstract excerpt

provides an unlimited resource for human CMs for a wide range of applications such as cell based cardiac repair, cardiac drug toxicology screening, and human cardiac disease modeling. However, their applicability is significantly limited by immature phenotypes. It has been well known that currently available CMs derived from hPSCs (hPSC-CMs) represent immature embryonic or fetal stage CMs and are functionally and...

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PMID: 29890820
DOI: 10.14348/molcells.2018.0143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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