Article
Hydrogel-based methods for engineering cellular microenvironment with spatiotemporal gradients
2 Feb 2015
Abstract excerpt
Natural cellular microenvironment consists of spatiotemporal gradients of multiple physical (e.g. extracellular matrix stiffness, porosity and stress/strain) and chemical cues (e.g. morphogens), which play important roles in regulating cell behaviors including spreading, proliferation, migration, differentiation and apoptosis, especially for pathological processes such as tumor formation and progression....
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