Article
Sex-dichotomous effects of NOS1AP promoter DNA methylation on intracranial aneurysm and brain arteriovenous malformation.
Neuroscience letters - 16 May 2016
Wang Zhepei, Zhao Jikuang, Sun Jie, Nie Sheng, Li Keqing, Gao Feng, Zhang Tiefeng, Duan Shiwei, Di Yazhen, Huang Yi, Gao Xiang
Abstract excerpt
The goal of this study was to investigate the contribution of NOS1AP-promoter DNA methylation to the risk of intracranial aneurysm (IA) and brain arteriovenous malformation (BAVM) in a Han Chinese population. A total of 48 patients with IAs, 22 patients with BAVMs, and 26 control individuals were enrolled in the study. DNA methylation was tested using bisulfite pyrosequencing technology. We detected significantly...
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