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Article

Genetic analysis of membrane cofactor protein (CD46) of the complement system in women with and without preeclamptic pregnancies.

PloS one - 1 Jan 2015

Lokki A Inkeri, Aalto-Viljakainen Tia, Meri Seppo, Laivuori Hannele

Abstract excerpt

Preeclampsia is a common disorder of pregnancy characterized by endothelial dysfunction. It may be life-threatening for the mother and fetus in severe cases. Dysregulation of the complement system has been suggested to predispose women to preeclampsia. Complement is part of the innate and adaptive immune systems and potentially capable of causing inflammation and tissue damage. Membrane cofactor protein MCP...

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PMID: 25710174
DOI: 10.1371/journal.pone.0117840
PMCID: PMC4339547

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