Article
A case of different gene mutations in primary and metastatic lesions after EGFR-TKI treatment of lung cancer.
Tumori - 1 Dec 2020
Xie Shaonan, Deng Huiyan, Liu Guangjie, Liu Qingyi
Abstract excerpt
BACKGROUND: It remains controversial whether patients with EGFR-mutant lung adenocarcinoma should stop using epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) after progression during treatment. CASE REPORT: We report a 35-year-old man with poorly differentiated adenocarcinoma of the left upper lobe and an exon 19 deletion (Ex19Del) mutation found by large-panel next-generation sequencing....
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