Article
Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Mar 2013
Ohashi Kadoaki, Maruvka Yosef E, Michor Franziska, Pao William
Abstract excerpt
PURPOSE: EGFR-mutant lung cancer was first described as a new clinical entity in 2004. Here, we present an update on new controversies and conclusions regarding the disease. METHODS: This article reviews the clinical implications of EGFR mutations in lung cancer with a focus on epidermal growth factor receptor tyrosine kinase inhibitor resistance. RESULTS: The discovery of EGFR mutations has altered the ways in...
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