Article
A Patient of Advanced NSCLC with a New EGFR Exon 19 Insertion Mutation and its Response to EGFR-TKIs.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP - 1 Dec 2019
Zhu Ning, Dong Caixia, Weng Shanshan, Yuan Ying, Yuan Ying
Abstract excerpt
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are the standard therapy for patients with advanced non-small-cell lung cancer (NSCLC) harbouring common EGFR mutations. However, about 10% of EGFR mutations are uncommon mutations and their response to EGFR-TKIs remains unclear. The present case reports a 75-year, female patient with advanced NSCLC, presenting with a new subtype of EGFR exon...
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