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Human Organoids: Tools for Understanding Biology and Treating Diseases

24 Sept 2019

Abstract excerpt

Organoids are in vitro-cultured three-dimensional structures that recapitulate key aspects of in vivo organs. They can be established from pluripotent stem cells and from adult stem cells, the latter being the subject of this review. Organoids derived from adult stem cells exploit the tissue regeneration process that is driven by these cells, and they can be established directly from the healthy or diseased...

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PMID: 31550983
DOI: 10.1146/annurev-pathmechdis-012419-032611

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