Article
A novel locus for exertional dyspnoea in childhood asthma.
The European respiratory journal - 1 Feb 2021
Lee Sanghun, Lasky-Su Jessica Ann, Lange Christoph, Kim Wonji, Kumar Preeti Lakshman, McDonald Merry-Lynn N, Vaz Fragoso Carlos A, Laurie Cecelia, Raby Benjamin A, Celedón Juan C, Cho Michael H, Won Sungho, Weiss Scott T, Hecker Julian
Abstract excerpt
Most children diagnosed with asthma have respiratory symptoms such as cough, dyspnoea and wheezing, which are also important markers of overall respiratory function. A decade of genome-wide association studies (GWAS) have investigated genetic susceptibility to asthma itself, but few have focused on important respiratory symptoms that characterise childhood asthma.Using whole-genome sequencing (WGS) data for 894...
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