Article
The long noncoding RNA FTX promotes a malignant phenotype in bone marrow mesenchymal stem cells via the miR-186/c-Met axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2020
Liu Liang, Li Xiaojian, Shi Yan, Chen Hua
Abstract excerpt
Gliomas are the most common and aggressive primary tumours of the central nervous system in adults. Bone marrow-derived mesenchymal stem cells (BMSCs) are an important component of the glioma microenvironment. Our previous study indicated that BMSCs in the glioma microenvironment could be induced to malignantly transform by glioma stem cells (GSCs). The malignant transformation of BMSCs is closely related to...
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