Article

The SRSF1/circATP5B/miR-185-5p/HOXB5 Feedback Loop Regulates the Proliferation of Glioma Stem Cells via the IL6-mediated JAK2/STAT3 Signaling Pathway

2020-12-15

Abstract excerpt

<h4>Background: </h4> Glioma is the most common and malignant tumor of central nervous system. The tumor initiation, self-renewal, and multi-lineage differentiation abilities of glioma stem cells (GSCs) are responsible for glioma proliferation and recurrence. Although circular RNAs (circRNAs) play vital roles in the progression of glioma, the detailed mechanisms remain unknown. MethodsqRT-PCR, western blotting, im...

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Literature Corpus work: 26db0601-3251-5aef-8968-10351a16ad40
DOI: 10.21203/rs.3.rs-125946/v1

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