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Innate immune molecular connections between atherosclerosis and statins: can the clinical laboratory venture beyond C-reactive protein?

American journal of clinical pathology - 1 Jan 2006

Staros Eric B

Abstract excerpt

Innate immunity was originally envisioned as a nonspecific host response to microbial pathogens. However, in the past few years, immunologists have discovered toll-like receptors (TLRs) and their role in recognizing pathogen-associated molecular patterns. TLRs and other components of innate immunity now help to explain the pathologic mechanisms underlying many common diseases, including atherosclerosis. At this...

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PMID: 16482986

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