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The epigenetic landscape of tumor-associated macrophages: orchestrating immune evasion in the tumor microenvironment

6 Aug 2025

Abstract excerpt

Tumor-associated macrophages (TAMs), the predominant immune cell population within the tumor immune microenvironment (TIME), play a vital role in promoting immune evasion and driving tumor progression. Beyond their well-established roles in reprogramming oncogenic signaling and silencing tumor suppressors, emerging evidence highlights that epigenetic modifications also critically shape the immunogenic landscape...

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PMID: 40780502
DOI: 10.1016/j.canlet.2025.217972

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